• William A. Tyndall MD PHD
  • (814) 942-1166
  • Location: Altoona (Fairway Drive), Huntingdon, DuBois
  • Specialty: Arthroscopy of the Shoulder, Elbow, Hip & Knee, Sports Medicine, Shoulder and Knee Replacements, General Orthopedics
  • Make an appointment


“I specialize in arthroscopy and joint replacements so that I can reduce the pain and improve the function in my patients.” – Dr. Tyndall

Dr. Tyndall is a Board Certified orthopedic surgeon who specializes in arthroscopy of the shoulder, knee, hip, elbow, and total joint replacements of the shoulder and knee. He is a fellowship trained in sports medicine and arthroscopy. He focuses on evaluating and diagnosing sports injuries and disorders of the upper and lower extremities, and providing effective treatment plans.

Dr. Tyndall is board certified through the American Board of Orthopedic Surgery. He is a fellow member of the American Academy of Orthopaedic Surgeons, Arthroscopy Association of North America, Orthopaedic Society for Sports Medicine, and Pennsylvania Orthopedic Society. He always considers traditional nonsurgical methods first to effectively relieve your pain. However, if surgery is necessary to allow you to resume a healthy lifestyle he will perform advanced, minimally invasive procedures that can lead you to a quicker and less painful recovery.

Dr. Tyndall resides in Hollidaysburg, PA with his wife Christine and their three children. They enjoy the outdoors, time with family, biking, running, and skiing.


  • 1986 J.P. McCaskey High School, Lancaster, PA-Valedictorian
  • 1990 Bachelor of Arts, Biochemistry (with honors), Brown University, Providence, RI
  • 1997 Doctor of Medicine and Doctor of Philosophy, Biochemistry and Molecular Biology (Seven year program), Thomas Jefferson University and Jefferson Medical College, Philadelphia, PA
  • 1997 internship and Residency: Department of Orthopedic Surgery, University of Medicine and Dentistry of New Jersey-University Hospital, Newark, NJ
  • 2002-2003 Sports Medicine Fellowship: Union Memorial Hospital, Baltimore, MD


American Board of Orthopaedic Surgery

Honors and Awards

  • 1986-1990 Honors degree in biochemistry, Honors-Medical Pharmacology
  • 1990-1997 Gibbon M.D./Ph.D. Scholarship to graduate/medical school, Honors-Internal Medicine Clerkship, American Society for Cell Biology Travel Award
  • 2000, 2001 AANA Resident Scholarships to Masters Arthroscopy Courses
  • 2001 NJOS Resident Research Award
  • 2001 Second Place NY-OREF Resident Research Symposium
  • 2001 AOA-Zimmer Travel Award for Orthopaedics
  • 2002 NJMS-Department of Orthopaedics-Resident Research Award



  • W. Andrew Tyndall, “The Effects of Selanazofurin and Tiazofurin on Phosphatidylinositol Turnover in Differentiated HL-60 Cells,” undergraduate honors thesis, Brown University, April 1, 1990.
  • W. Andrew Tyndall, “Effect of TGF-Beta Superfamily Members on Limb Mesenchyme Chondrogenesis In Vitro: Modulation of N-Cadherin and Catenin Expression and Association,” Ph.D. Research, Thomas Jefferson University, August 4 1995.


  • Moberg, K.H., Tyndall, W.A., Pyrc, J., and Hall, D.J. (1991), “Analysis of the c-myc P2 promoter,” J. Cell. Physiol. 148(1):75-84.
  • Ballard, J.J., Tyndall, W.A., Shingle, J.M., Hall, D.J., and Winter, E. (1991), “Tyrosine phosphorylation of yeast 40 kDa protein occurs in response to mating pheromone,” EMBO J. 10(12):3753-3758.
  • Moberg, K.H., Tyndall, W.A., and Hall, D.J. (1992), “Wild-type murine p53 represses transcription from the murine c-myc promoter in human glial cell line,” J. Cell. Biochem. 49(2):208-215
  • Moberg, K.H., Logan, T.J., Tyndall, W.A., and Hall, D.J. (1992), “Three distinct elements within the murine c-myc promoter are required for transcription,” Oncogene 7(3):411-421.
  • Tyndall, W.A., Beam, H.A., Zarro, C., O’Connor, P., and Lin, S.S. (2002), “Decreased PDGF expression during Diabetic Fracture Healing,” Clin. Orthop. 408:319-30.
  • Bibbo, C., Patel, D.V., Tyndall, W.A., Sirkin, M.S., and Chang, V. (2003), “Treatment of multifocal vancomycin-resistent enterococus faecium osteomyelitis in sickle cell disease: a preliminary report,” Am. J. Orthop. 32(10): 505-9.


  • Tyndall, W.A. and Tuan, R.S., “Involvement of N-cadherin mediated cell adhesion in the biphasic effects of TGF-Beta1 on limb mesenchyme chondrogenesis,” Orthopedic Research Society Annual Meeting, San Francisco, CA, 1995.
  • Tyndall, W.A. and Tuan, R.S., “Effect of TGF-Beta1 and BMP-2 on limb mesenchyme chondrogenesis in vitro: modulation of N-cadherin and catenin association,” Orthopedic Research Society Annual Meeting, Orlando, FL, 1996.
  • Tyndall, W.A., Beam, H.A., Zarro, C., and Lin, S.S., “Characterization of Deficient Fracture Healing in Experimental Diabetes,” Association of Cone and Joint Surgeons Annual Meeting, San Antonio, TX, 2000.
  • Tyndall, W.A., Beam, H.A., Zarro, C., and Lin, S.S., “Characterization of Deficient Fracture Healing in Experimental Diabetes,” New Jersey Orthopaedic Society Annual Meeting, Piscataway, NJ, 2000.
  • Tyndall, W.A., Beam, H.A., Zarro, C., Lin, S.S., “Characterization of Deficient Fracture Healing in Experimental Diabetes,” AOA-Residents Meeting, Hershey, PA, 2001.
  • Tyndall, W.A., Beam, H.A., Zarro, C., Lin, S.S., “Characterization of Deficient Fracture Healing in Experimental Diabetes,” NY-OREF Resident Research Symposium, New York, NY, 2001.
  • Tyndall, W.A., Beam, H.A., Zarro, C., O’Connor, P., Lin, S.S., “Decreased PDGF Expression during Diabetic Fracture Healing,” New Jersey Orthopaedic Society Annual Meeting, Woodbridge, NJ, 2001.



Hospital and Surgical Affiliations

  • UPMC Altoona
  • JC Blair Memorial Hospital
  • Tyrone Hospital
  • Penn Highlands Hospital - DuBois Regional Medical Center
  • Nason Hospital
  • Advanced Center for Surgery

Professional Organizations

  • American Academy of Orthopaedic Surgeons
  • Arthroscopy Association of North America
  • Orthopaedic Society for Sports Medicine
  • Pennsylvania Orthopedic Society
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